Prevalence and risk factors of healthcare-associated diarrhea in a large pediatric hospital in Arkhangelsk, Northwest Russia
METHODS: We performed a cohort study including all patients treated in infectious ward during 2012. Patients with length of stay less than 48 hours were excluded from the study according to the definition of healthcare associated infections. Risk factors for healthcare-associated diarrhea were searched by using multivariate logistic regression analysis.
RESULTS: Altogether 1852 patients were enrolled. The incidence of healthcare-associated diarrhea was 9.1 per 100 admissions. Rotavirus was detected in 60.9% of the cases. Compared to infants, children aged 1-3 years (OR=0.5, 95% CI: 0.4-0.8) and older 3 years (OR=0.3, 95% CI: 0.2-0.5) were less likely to have HAI. Hospital stay 8-14 days (OR=4.8, 95%CI: 3.1-7.4) and more then 14 days (OR=8.5, 95% CI: 4.6-15.5) was associated with HAI compared to stay for less than 7 days. Admission during winter-spring season (OR=3.0, 95% CI: 1.6-5.6) and presence of a relative caring for the patient (OR=3.7, 95% CI: 1.6-8.8) were positively associated with HAI.
CONCLUSIONS: Nine out of a hundred patients hospitalized in the typical infectious ward of the large Russian pediatric hospital gets healthcare-associated diarrhea. Young age (less than 1 year), longer hospitalization time (more than 7 days), admission during winter-spring season and presence of a relative caring for the patient were found to be risk factors.