Metabolic Syndrome (Ms) among Xavante Indians from Central Brazil

Dal Fabbro, Amaury

Metabolic Syndrome (Ms) among Xavante Indians from Central Brazil

Tuesday, 19 August 2014

Exhibit hall (Dena'ina Center)

Amaury L Dal Fabbro, MD , Ribeirão Preto Medical School - University of São Paulo, Ribeirão Preto, Brazil

Laercio J Franco, MD , Ribeirão Preto Medical School - University of São Paulo, Ribeirão Preto, Brazil

Daniela S Sartorelli, PhD , Ribeirão Preto Medical School - University of São Paulo, Ribeirão Preto, Brazil

Anderson S Silva, MD , Ribeirão Preto Medical School - University of São Paulo, Ribeirão Preto, Brazil

Luana P Soares, MPH , Ribeirão Preto Medical School - University of São Paulo, Ribeirão Preto, Brazil

Luciana F Franco, MD , Escola Paulista de Medicina - Federal University of São Paulo, São Paulo, Brazil

Patricia C Kuhn, MD , Escola Paulista de Medicina - Federal University of São Paulo, São Paulo, Brazil

Regina S Moises, MD , Escola Paulista de Medicina - Federal University of São Paulo, São Paulo, Brazil

João Paulo B Vieira-Filho, MD , Escola Paulista de Medicina - Federal University of São Paulo, São Paulo, Brazil

INTRODUCTION: Xavante Indians live in an area from Central Brazil. After contact with members of the Brazilian Society, this new condition produced important changes in their traditional way of life, incorporating new foods such as rice, resulting in obesity (50.8%) and diabetes mellitus (28.2%), especially among women. Aims: To analyze the prevalence of Ms among adults aged 20 years or more according to gender and two diagnostic criteria of Ms: IDF 2005 and ATPIII 2001.

METHODS: population-based survey was carried out among 948 Xavante. Fasting and 2-hour after 75g glucose capillary were measured by a portable glucometer (HemoCue® Glucose201) (WHO criteria) in the Sangradouro and São Marcos Reservations, Mato Grosso State, Brazil. Anthropometric data and medical characteristics were measured, like waist circumference. Blood pressure was measured by an automated device (OMRON 7421INTC®), and hypertension was defined according WHO criteria. Blood samples were collected for laboratory tests of HDL-c and Triglycerides (TG).

RESULTS: according to IDF criteria the prevalence of Ms was: 64.2% in general (61.2-67.3), 52.6% (48-57.1) in men and 75.3% (71.5-79.2) in women (p<0.05); among individuals with Ms, 86.1% had reduced HDL-c, 70.1% had raised TG, 24.1% had hypertension and 78% had diabetes mellitus (DM) or Impaired Glucose Tolerance (IGT). According to ATPIII criteria, prevalence of Ms was: 45% in general (43.7-50.1), 23.9% (20.0-27.8) in men and 69.1% (65.0-73.2) in women (p<0.05); among individuals with Ms, 91.9% had reduced HDL-c, 70.0% had raised TG, 23.7% had hypertension and 80.6% had DM or IGT.

CONCLUSIONS: IDF and ATPIII criteria produced different results in the prevalence of Ms, especially in men. Ms is an important risk factor to cardiovascular disease and high prevalence rates of Ms were observed among Xavante Indians. Preventive and control measures need to be implemented in this population.