A retrospective prospective cohort in Japanese -SAKU Cohort Study -

INTRODUCTION:  Recently type 2 diabetes mellitus (T2DM) and metabolic syndrome (MetS) has been focused in Japan. Lifestyle modifications have become major strategies for prevention of obesity as a strong risk factor for these diseases. However, the long-term effect of lifestyle to prevent, or develop these diseases is not well understood. To evaluate the effects of long-term lifestyle and it’s modification on T2DM and MetS, we launched a retrospective and prospective cohort of Japanese men and women.

METHODS:  Japanese men and women were enrolled from January 2009 to March 2012 in our cohort - Saku Cohort Study - from those who had undergone medical checkups in the Saku Central Hospital. They received an .anthropometric and clinical examination and assessed for present illness, lifestyle such as physical activities, smoking, drinking, and dietary habits at the enrollment.

RESULTS: 4450 subjects (2604 men and 1846 women) were enrolled. The mean age was 58.9 years and the mean body mass index was 23.1 kg /m². The percentages of the person suspected of T2DM and MetS were 10.3 % and 9.5 %, respectively.  

CONCLUSIONS:  The percentages of T2DM and MetS in our cohort were not higher than Japanese average. Almost all participants have been received medical checkups every years. We would collect their retrospective data and prospective data in medical checkups continuously and analyze the relationship between these diseases and lifestyle.