Pancreatic cancer in Niamey: first results from a population-based cancer registry

Wednesday, 20 August 2014
Exhibit hall (Dena'ina Center)
Salamatou Mamoudou Garba , Laboratory of Genetics and Biometry, Faculty of Science, Ibn Tofaïl University, Kenitra, Morocco
Hinde Hami , Laboratory of Genetics and Biometry, Faculty of Science, Ibn Tofaïl University, Kenitra, Morocco
Harouna Mahamadou Zaki , Laboratory of Pathological Anatomy and Cytology, Faculty of Health Sciences, Abdou Moumouni University, Niamey, Niger
Abdelmajid Soulaymani , Laboratory of Genetics and Biometry, Faculty of Science, Ibn Tofaïl University, Kenitra, Morocco
Hassan Nouhou , Laboratory of Pathological Anatomy and Cytology, Faculty of Health Sciences, Abdou Moumouni University, Niamey, Niger
Ali Quyou , Laboratory of Genetics and Biometry, Faculty of Science, Ibn Tofaïl University, Kenitra, Morocco
INTRODUCTION: Pancreatic cancer is an uncommon cancer in Western Africa. It is the 12th most commonly diagnosed cancer and the ninth most common cause of cancer death in both men and women, with an estimated 2 673 new cases of pancreatic cancer (1.5% of the total) and 2 565 cancer deaths in 2012 (2% of the total) (GLOBOCAN 2012). The aim of the present study is to determine the epidemiological characteristics of pancreatic cancer in Niamey, capital of the Niger.

METHODS: This is a retrospective study of pancreatic cancer cases, reported between 1992 and 2009 to the Niger Cancer Registry, established in 1992, in the Faculty of Health Sciences at the Abdou Moumouni University in Niamey.  

RESULTS: A total of 59 cases were diagnosed with pancreatic cancer in Niamey, which was 1.2% of all cancers reported during the study period. Nearly two-thirds of the cases (64.4%) were men with a male-female ratio of 1.81. The average age at diagnosis of pancreatic cancer was 54.7±14.7 years. More than 84% of people diagnosed with the disease were aged 40 years or older at the time of diagnosis, with 76.3% of new cancer cases occurring among those aged 40-74 years. The risk of developing pancreatic cancer varied among various ethnic groups. Djerma-Sonrai was more likely to develop pancreatic cancer than any other ethnic groups. Among all diagnosed cases, 11 (18.6%) died during the study period, accounting for 1.7% of all cancer deaths. 

CONCLUSIONS: Pancreatic cancer remains a significant public health issue. Early diagnosis is difficult because the disease is asymptomatic in its early stages "silent disease".